Stem Cell Treatment for Stroke-Related Disability
PISCES III is a randomized, placebo-controlled, multi-center study to evaluate whether injecting neural stem cells into the brain near the area affected by a stroke can help reduce stroke-related disability.
Patients with persistent disability 6-12 months following an ischemic stroke may be eligible to participate. Enrolled patients will be randomized 1:1 to undergo a stereotactic surgery and receive a single administration of CTX0E03 Drug Product by intracerebral implantation or undergo sham surgery only (placebo).
Patients will be followed for 12 months after surgery with follow-up assessments occurring at various time points over the 12 months.
All eligible patients will be assigned a standardized Physical Therapy (PT) program and complete daily PT exercises at home for 12 weeks after their surgery.