We are dedicated to improving the lives of patients with challenging neurological conditions. In addition to delivering exceptional care with standard techniques, our team is involved in clinical research studies that test new treatments and approaches.
Research studies at Duke are overseen by the Duke Office of Clinical Research. Studies can be funded by Duke, external grants, and/or industry sponsors. The Duke Institutional Review Board examines the ethical implications of the study design and anticipated outcomes for all clinical trials conducted at Duke.
Below are some of the clinical trials we have been involved in. If you are interested in participating in a research study, our research staff can provide up-to-date information and assess your eligibility for enrollment.
Together with our patients and research collaborators, we believe we can make a dramatic impact by participating in translational research, understanding the economic implications of various conditions and treatments, and helping to develop new innovations that advance the standard of care.
Current Clinical Trials
HF10 Spinal Cord Stimulation for Chronic Back Pain
This study compares HF10 spinal cord stimulation to conventional medical management alone for chronic back pain. It is for patients with non-surgical refractory back pain (NSRBP) who are not considered candidates for spine surgery.
Peripheral Nerve Stimulation for Chronic Low Back Pain
This study evaluates the safety and effectiveness of peripheral nerve stimulation (PNS) on low back pain. It involves the FDA-approved SPRINT PNS system.
Stem Cell Treatment for Stroke-Related Disability
This study, called PISCES III, evaluates whether injecting neural stem cells into the brain near the area affected by a stroke can help reduce stroke-related disability.
Previous Clinical Trials
HF10 Spinal Cord Stimulation for Painful Diabetic Neuropathy
This study compares HF10 spinal cord stimulation to conventional medical management alone for painful diabetic neuropathy (PDN).
ReActiv8 Neurostimulation for Chronic Low Back Pain
This study evaluates the safety and efficacy of the ReActiv8 implantable neuromodulation system for chronic low back pain.
Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome
This study evaluates the continued safety of the Axium Neurostimulator System for dorsal root ganglion (DRG) stimulation. It is for patients with chronic lower-limb pain due to complex regional pain syndrome (CRPS).