Clinical Research

Research studies at Duke are conducted by a principal investigator and can include grant funded research and /or industry sponsored clinical research. Dr. Lad works closely with the Duke Office of Clinical Research (DOCR) which oversees the conduct of clinical research. The Duke Institutional Review Board web site contains information about participating in clinical research at Duke. Dr. Lad’s research staff can also provide up-to-date information regarding a number of current clinical trials and research studies that you may be interested in.

We believe in supporting the best students, residents and faculty collaborators that are passionate about improving the lives of patients with challenging neurological conditions. There's a lot to learn and together we can make a dramatic impact by participating in translational research (that actually translates), understanding the health economics of various conditions and helping develop new innovations that advance our current standard of care.


Current Research Topics

Mainstay ReActiv8-B for Chronic Low Back Pain

Objective: To determine the safety and efficacy of ReActiv8 for the treatment of adults with chronic low back pain and no previously spinal surgery. This treatment is used in addition to medical management.


TARGET (Abbott) DRG treatment for lower-limb CRPS Types I and II

Objective:  To demonstrate continued safety of the Axium Neurostimulator System for dorsal root ganglion (DRG) stimulation.


SPR PNS for Chronic Low Back Pain

Objective: To evaluate the safety and effectiveness of peripheral nerve stimulation (PNS) on low back pain.


Nevro PDN-1 Study (HF10 for Painful Diabetic Neuropathy)

Objective: To document comparative safety, clinical effectiveness, and cost effectiveness of the addition of HF therapy to CMM in comparison to CMM alone in subjects with painful diabetic neuropathy (PDN).

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